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ACE-031

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PRODUCT PROFILE

Product
Information

ACE-031 (ramatercept) is a soluble ActRIIB-IgG1 Fc fusion (myostatin/activin ligand trap). Supplied as a research reagent. For laboratory research use only.

TECHNICAL PROFILE

Specifications

Product-specific technical information and handling details.

Purity
≥99% (HPLC / stated assay)
Form
Lyophilized recombinant protein (ActRIIB-Fc)
Content
1 mg
Concentration
Depends on reconstitution volume Example: 1 mg in 1 mL = 1 mg/mL
Volume
Reconstitute as required for the intended assay
Packaging
Sealed sterile glass vial with rubber stopper and flip-off cap
Storage
Lyophilized: −20 °C, protected from light. After reconstitution: 2–8 °C. Do not shake hard (protein). Avoid freeze–thaw.
Molecular Formula
Not applicable (recombinant glycoprotein fusion)
Molecular Weight
~58–77 kDa per chain / ~110–180 kDa as Fc homodimer (glycosylation-dependent)
Sequence
Human ActRIIB extracellular domain fused to human IgG1 Fc
CAS Number
1169766-01-1 (ramatercept / ACE-031)
RESEARCH PROFILE

Research
Overview

Studied as a decoy receptor for ActRIIB ligands (myostatin, activins, GDF-11) in muscle-biology models. Research-use material only. Not for human or veterinary use, diagnostic use, or consumption.

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